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日糧維E對斷奶仔豬影響的研究報告


日糧維E抑制空腸上皮細胞增殖,進而影響腸道形態、消化酶活性和養分轉運因子

澳门新葡8455最新网站 Cancan Chen Zhaobin Wang Jianzhong Li Yali Li Pengfei Huang Xueqin Ding Jia Yin Shanping He Huansheng Yang Yulong Yin

維E是仔豬日糧配方中不可缺少的維生素之一。除此之外,它影響著小腸組織,尤其是腸道上皮細胞的功能。前人的研究很少關注維E對腸道組織影響(尤其是消化吸收方面)。已經證實維E可以抑制一些細胞的分化。相關閱讀:仔豬腸道健康的福音--斯福

本試驗在于研究維E是否通過影響腸道細胞的分化進而影響腸道功能。試驗選用30頭21日齡斷奶仔豬(約克夏×杜洛克),初始重6.36±0.55kg,隨機分為5個處理組。分別為:對照組(0 IU)、16 IU、32 IU、80 IU、160 IU。試驗期14天。試驗結束后,屠宰試驗動物,收集血液和組織樣品。


維E,維生素E

(圖:維E)

澳门新葡8455最新网站 試驗結果表明維E不影響動物生長性能。維E可以提高空腸隱窩深度(線性,P=0.056)和絨毛寬度(線性,P<0.05)。與對照組相比,80IU維E組蔗糖酶活性顯著降低(P<0.05)。并且空腸隱窩深度和細胞分化也有顯著降低(P<0.05)。

試驗說明日糧維E可能抑制斷奶仔豬空腸上皮細胞增殖,進而影響腸道形態和功能。

Dietary vitamin E affects small intestinal histomorphology, digestive enzyme activity, and the expression of nutrient transporters by inhibiting proliferation of intestinal epithelial cells within jejunum in weaned piglets

Cancan Chen Zhaobin Wang Jianzhong Li Yali Li Pengfei Huang Xueqin Ding Jia Yin Shanping He Huansheng Yang Yulong Yin

Vitamin E (VE) is an indispensable vitamin in piglet feed formula. Among other things, it affects tissues including small intestine tissues and in particular its major unit intestinal epithelial cells. Previously, limited in vivo experiments have focused on the effect of VE on the intestine, particularly digestion and absorption. VE has been shown to inhibit proliferation of some types of cells. This experiment was conducted to test the hypothesis that VE affects intestinal functions by influencing the intestinal epithelial cell proliferation. Thirty 21-d old weaned [(Yorkshire × Landrace) × Duroc] piglets with BWs of 6.36 ± 0.55 kg were randomly divided into five VE-containing feeding formula groups. The treatments were (i) 0 IU (control), (ii) 16 IU, (iii) 32 IU, (iv) 4. 80 IU, and (v) 5. 160 IU. The treatments lasted 14 d. At the end of the experiment, all subjects were sacrificed to obtain blood and tissue samples. The results suggest that VE did not affect the growth performance. VE did tend to decrease jejunal crypt depth (linear, P = 0.056) and villus width (linear, P < 0.05). Sucrase activity significantly decreased in the adding 80 IU VE compared with the control (P < 0.05). Jejunal crypt, cell proliferation in 80 IU group significantly decreased compared with the control group (P < 0.05). This study suggests that dietary VE may affect intestinal morphology and functions by inhibiting weaned piglet jejunal epithelial cell proliferation.

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